Susan P Perrine Selected Research

gamma-Globins

4/2014	Targeted fetal hemoglobin induction for treatment of beta hemoglobinopathies.
8/2010	Fetal globin gene inducers: novel agents and new potential.
11/2006	Short-chain fatty acids induce gamma-globin gene expression by displacement of a HDAC3-NCoR repressor complex.
5/2006	Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models.
12/2002	Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo.

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Susan P Perrine Research Topics

Disease

10	Thalassemia 04/2014 - 01/2005
9	Hemoglobinopathies 01/2016 - 12/2002
7	Anemia 01/2016 - 12/2002
6	Sickle Cell Anemia (Hemoglobin S Disease) 04/2014 - 10/2003
6	beta-Thalassemia (Cooley's Anemia) 08/2011 - 01/2005
5	Neoplasms (Cancer) 08/2012 - 03/2006
4	Lymphoma (Lymphomas) 01/2012 - 03/2006
2	Prostatic Neoplasms (Prostate Cancer) 08/2012 - 09/2011
1	Obesity 08/2012
1	Hematologic Diseases (Blood Diseases) 08/2012
1	Insulin Resistance 08/2012
1	Herpesviridae Infections (Herpesvirus Infection) 01/2012
1	Leg Ulcer 12/2010
1	Seizures (Absence Seizure) 07/2009
1	Sleepiness 03/2007
1	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2007
1	Cystic Fibrosis (Mucoviscidosis) 03/2006
1	Neutropenia 03/2006
1	Hepatitis 03/2006
1	Massive Hepatic Necrosis 03/2006
1	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 06/2003

Drug/Important Bio-Agent (IBA)

12	GlobinsIBA 01/2016 - 01/2005
6	arginine butyrateIBA 01/2012 - 06/2003
5	gamma-GlobinsIBA 04/2014 - 12/2002
5	Butyrates (Butyrate)IBA 08/2012 - 01/2005
4	2,2-dimethylbutyric acidIBA 03/2014 - 08/2011
4	Ganciclovir (Cytovene)FDA LinkGeneric 01/2012 - 03/2006
4	Proteins (Proteins, Gene)FDA Link 01/2007 - 01/2005
3	Fetal Hemoglobin (Hemoglobin F)IBA 04/2014 - 08/2011
3	alpha-GlobinsIBA 04/2014 - 01/2005
3	NucleosidesIBA 01/2012 - 01/2007
3	Antiviral Agents (Antivirals)IBA 01/2012 - 01/2007
3	Volatile Fatty AcidsIBA 05/2006 - 01/2005
2	Histone Deacetylases (Histone Deacetylase)IBA 08/2012 - 01/2012
2	DNA (Deoxyribonucleic Acid)IBA 08/2012 - 01/2007
2	Vorinostat FDA Link 01/2012 - 09/2011
2	Hemoglobins (Hemoglobin)IBA 08/2010 - 01/2005
2	Thymidine KinaseIBA 03/2007 - 01/2007
2	Erythropoietin FDA Link 01/2005 - 01/2005
1	Mi-2 Nucleosome Remodeling and Deacetylase ComplexIBA 01/2016
1	Sickle HemoglobinIBA 11/2013
1	SodiumIBA 11/2012
1	Fatty Acids (Saturated Fatty Acids)IBA 08/2012
1	Messenger RNA (mRNA)IBA 08/2012
1	Telomerase (Telomerase Reverse Transcriptase)IBA 08/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	Histone Deacetylase InhibitorsIBA 01/2012
1	belinostatIBA 01/2012
1	Butyric Acid (Butanoic Acid)IBA 09/2011
1	Hemoglobin AIBA 08/2011
1	Valproic Acid (Depakote)FDA LinkGeneric 07/2009
1	4-phenylbutyric acid (Buphenyl)FDA Link 01/2008
1	Azacitidine (5 Azacytidine)FDA Link 01/2008
1	Decitabine FDA Link 01/2008
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2008
1	EnzymesIBA 03/2007
1	Drug CombinationsIBA 03/2007
1	Biological ProductsIBA 03/2007
1	ChromatinIBA 11/2006
1	Therapeutic UsesIBA 05/2006
1	Phenylalanine (L-Phenylalanine)FDA Link 03/2006
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 03/2006
1	ChloridesIBA 03/2006
1	Fas Ligand Protein (Fas Ligand)IBA 03/2006
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2005
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2003

Therapy/Procedure

8	Therapeutics 04/2014 - 01/2005
1	Salvage Therapy 03/2006